Sigma-Aldrich

Sigma-Aldrich (operating as MilliporeSigma in the U.S. and Canada) is an American chemical, life sciences, and biotechnology company headquartered in St. Louis, Missouri, United States. Formed in 1975 by the merger of Sigma Chemical Company and Aldrich Chemical Company, it was acquired by Merck KGaA in 2015 for $17 billion and now forms part of Merck's Life Science business. The company supplies over 300,000 products, luding reagents, biochemicals, organic chemicals, labware, and analytical tools for research, pharmaceutical development, and biopharma manufacturing. Its segments cover research essentials, applied solutions, and integrated services like contract testing via BioReliance. Sigma-Aldrich operates in over 40 countries with manufacturing in the U.S., Europe, and Asia, partnering with global suppliers for raw materials while complying with REACH, TSCA, and GMP regulations. It emphasizes sustainability through green chemistry and waste reduction. In 2024, as part of Merck KGaA, it contributed to life science revenues of €8.5 billion, focusing on biologics and AI-driven discovery tools.